Optimal degrees of synaptic connectivity
http://www.columbia.edu/cu/neurotheory/Larry/ WebSparse synaptic wiring can optimize a neural representation for associative learning • Maximizing dimension predicts the degree of connectivity for cerebellum-like circuits • Supervised plasticity of input connections is needed to exploit dense wiring • Performance of a Hebbian readout neuron is formally related to dimension
Optimal degrees of synaptic connectivity
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WebNeuron Article Optimal Degrees of Synaptic Connectivity Ashok Litwin-Kumar, 1 ,9 * Kameron Decker Harris,2 Richard Axel, 3 4 Haim Sompolinsky,5 6 7 and L.F. Abbott1,8 … http://lk.zuckermaninstitute.columbia.edu/pdf/litwin-kumar_optimal_2024.pdf
WebMar 11, 2024 · Optimal degrees of synaptic connectivity ( Litwin-Kumar et al., 2024) could be then associated with dendritic length and branching pattern, spine features, and the neuronal impedance, conductance, and voltage modulatory properties ( Papoutsi et … WebRecent work will be discussed that addresses what determines the optimal number of connections for a given neuronal type, and what these different degrees of connectivity …
WebOptimal Degrees of Synaptic Connectivity. Litwin-Kumar A, Harris KD, Axel R, Sompolinsky H, Abbott LF. Neuron.2024 Mar 8. Inhibitory stabilization and visual coding in cortical … WebJan 23, 2014 · In contrast, baseline synaptic connectivity strengths were consistently strong over the decades. Our findings suggest that the lifetime accrual of sensory experience optimizes functional brain architectures to enable efficient and generalizable predictions of the world. Author Summary
WebOur theory predicts that the dimensions of the cerebellar granule-cell and Drosophila Kenyon-cell representations are maximized at degrees of synaptic connectivity that …
WebMar 1, 2005 · Results. We studied connectivity among thick tufted layer 5 neurons in rat visual cortex with quadruple whole-cell recordings (Figure 1A and 1B).Thick tufted layer 5 pyramidal neurons are important projection neurons from the cerebral cortex to subcortical areas [9,31,32].Synaptic connection strengths were assessed by evoking action potentials … how to remove moss from tarmac driveWebconnectivity and synaptic weights of cortical neuron cultures at different days in vitro from multielectrode array recordings. Using a stochastic leaky-integrate-and-fire model, how to remove moss on roof shinglesWebFeb 1, 2024 · Moreover, analyzing the functional organization of population neurons has shown that both the in- and out-degree of synaptic connectivity are broadly distributed with heavy tails Bonifazi et al., 2009, Ito et al., 2014, ... Optimal degrees of synaptic connectivity. Neuron, 93 (2024), pp. 1153-1164. e1157. View in Scopus Google Scholar. how to remove moss from tarmac drivewayWebOptimal degrees of synaptic connectivity. Neuron 93 (5), 1153–1164. A. Litwin-Kumar, R. Rosenbaum & B. Doiron (2016). Inhibitory stabilization and visual coding in cortical … how to remove moss from stoneWebDec 8, 2024 · Abstract. Studies of brain network connectivity improved understanding on brain changes and adaptation in response to different pathologies. Synaptic plasticity, the ability of neurons to modify their connections, is involved in brain network remodeling following different types of brain damage (e.g., vascular, neurodegenerative, inflammatory). how to remove moss from your yardWebOptimal Degrees of Synaptic Connectivity Synaptic connectivity varies widely across neuronal types. In the cerebellar cortex, granule cells receive five orders of magnitude fewer inputs than the Purkinje cells they innervate. A large divergence in synaptic connectivity is also seen in other circuits with cerebellum-like architectures, including ... noritake colorwave tablecloth clayWebThe theory I will describe predicts optimal values for the number of inputs to cerebellar granule cells and Kenyon cells of the Drosophila mushroom body, and it also provides a … how to remove moss from wood