Cyclic pifithrin-α hydrobromide
WebSep 16, 2005 · Abstract. The small-molecule compound pifithrin-α (PFT-α) has been reported to inhibit p53 function and protect against a variety of genotoxic agents. We show here that PFT-α is unstable in tissue culture medium and is rapidly converted to its condensation product PFT-β. Both compounds showed limited solubility with PFT-α … WebPifithrin-α is a reversible inhibitor of p53-mediated apoptosis and p53-dependent gene transcription such as cyclin G, p21/waf1, and mdm2 expression. Pifithrin-α enhances …
Cyclic pifithrin-α hydrobromide
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Web购物车是空的！ 多肽产品 抗体抑制剂 染料试剂 PROTAC 虚拟筛选 TargetMol试剂盒 Cell Counting Kit-8 (CCK-8) Inhibitor Cocktails 天然产物 酚类 生物碱 类黄酮 实验仪器 WebCyclic Pifithrin-α hydrobromide Synonym(s): 2-(4-Methylphenyl)imidazo[2,1-b]-5,6,7,8-tetrahydrobenzothiazole hydrobromide, Pifithrin-α, cyclic, Cyclic PFT-α hydrobromide, QB102 Empirical Formula (Hill Notation): C16H16N2S · HBr CAS No.: 511296-88-1 Molecular Weight: 349.29 Compare Product No. Description SDS Pricing P4236 ≥98% …
WebPifithrin-α is firstly found to block the activation of p53-responsive lacZ in ConA cells and reduce activation of endogenous cellular p53-responsive genes. In MEF cells transformed with E1a+ras, 10μM Pifithrin-α can inhibit the apoptosis of the cells and this anti-apoptotic activity is p53-dependent. Web丁香通为您提供Dibenzylfluo商品详情介绍：价格：￥455 - 7397，货号：C3305，品牌：APExBIO，详见丁香通Dibenzylfluo商品详情页；
WebCyclic Pifithrin- α hydrobromide is a cyclic analog of pifithrin- α (Cat. No. 1267), a small molecule inhibitor of p53. Prevents dexamethasone -induced cell death in murine … WebCyclic Pifithrin-α (hydrobromide) from Cayman Chemical. Be the first to write a review! Citations: Description A stable analog of PFT-α, formed by the condensation of PFT-α in …
WebProduct Name: Cyclic Pifithrin-α hydrobromide Synonyms: Pifithrin-β Formula: C16H16N2S.HBr Molecular Weight: 349.29 CAS Number: 511296-88-1 4. FIRST AID MEASURES 4.1 Description of first aid measures General advice Consult a doctor and show this safety data sheet. If inhaled Remove to fresh air and monitor breathing.
WebCyclic Pifithrin-α hydrobromide Synonym(s): 2-(4-Methylphenyl)imidazo[2,1-b]-5,6,7,8-tetrahydrobenzothiazole hydrobromide, Cyclic PFT-α hydrobromide, Pifithrin-α, cyclic, QB102 Empirical Formula (Hill Notation): C16H16N2S · HBr CAS No.: 511296-88-1 Molecular Weight: 349.29 Compare Product No. Description SDS Pricing P4236 ≥98% … how do you buy a wheeler dealer carWebThis small molecule/inhibitor is primarily used for Activators/Inducers applications. Pricing and availability is not currently available. Properties Quality Level 100 form solid manufacturer/tradename Calbiochem® storage condition OK to freeze desiccated (hygroscopic) protect from light solubility DMSO: soluble (supplied) shipped in wet ice how do you buy altcoinsWebCyclic Pifthrin-Alpha is a cell-permeable and reversible inhibitor of p53-mediated apoptosis and p53-dependent gene transcription. It is a more stable and less cytotoxic analog of the non-cyclic form of pifithrin-alpha. … pho madison wiWebPifithrin-α hydrobromide is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of … how do you buy and atm machineWebCyclic Pifithrin-α hydrobromide has been used as p53 inhibitor to study its role in cigarette smoke−induced apoptosis of pulmonary endothelial cells. Confezionamento 5, 10 mg in glass bottle Protect from light. Azioni biochim/fisiol A stable analog of Pifithrin-α (Product Code P4359) with similar biological activities and lower cellular toxicity. pho madison menuWebPifithrin-μ A cell-permeable sulfonamide that blocks p53 interaction with Bcl-xL and Bcl-2 proteins and selectively inhibits p53 translocation to mitochondria without affecting the transactivation function of p53. Synonym (s): Pifithrin-μ, Phenylacetylenylsulfonamide, Hsp70 Inhibitor I Empirical Formula (Hill Notation): C8H7NO2S CAS Number: pho madison st seattleWebProduct name Cyclic Pifithrin-alpha hydrobromide, pifithrin-alpha analog Description Stable, cell-permeable analog of pifithrin-α. p53 inhibitor Biological description Stable, … how do you buy and sell bonds